Long-term Outcomes And Survival Predictors In Patients With Ectopic ACTH Syndrome: Data From A Retrospective Cohort Study.

Background: Ectopic ACTH syndrome (EAS) is caused by non-pituitary neuroendocrine tumor (NET) which produces adrenocorticotropic hormone (ACTH).

Objective: To identify survival predictors and to analyze long-term outcomes in patients with EAS.

Methods: Medical records of patients with verified EAS between 1990 and 2024 were analyzed to obtain the initial clinical and biochemical data along with subsequent interventions and survival outcomes.

Study of Adhesion-Cohesive Interactions of Modified Bitumen Compositions.

The aim of the work was to study the effect of additive concentration on changes in the adhesive and cohesive strength of bitumen. To evaluate the effectiveness of modifiers in the composition of binary and triple bitumen systems in relation to mineral fillers of two grades, the method of determination of the adhesive efficiency and thermodynamic calculations of adhesion and cohesion work were used. The following compounds were used as additives: synthesized from the oil refining waste and (waste sealing liquid).

Secondary structure analysis of proteins within the same topology group.

The native conformation of a protein plays a decisive role in ensuring its functionality. It is established that the spatial structure of proteins may exhibit a greater degree of conservation than the corresponding amino acid sequences. This study aims to clarify structural distinctions between homologous and non-homologous proteins with identical topology.

The Effect of the Microstructure and Viscosity of Modified Bitumen on the Strength of Asphalt Concrete.

The purpose of these studies was to establish the influence of the microstructural and rheological characteristics of modified bitumen compositions on the strength indicators of asphalt concrete. The effect of additives concentration on the rheological characteristics and microstructure of binary "bitumen-surfactant", "bitumen-AG-4I", and ternary "bitumen-AG-4I-AG-4I" systems has been studied. To assess the effect of bitumen dispersion on the physical and mechanical characteristics of modified asphalt concrete samples, the compressive strength value was determined.

Increasing the Adhesion of Bitumen to the Surface of Mineral Fillers through Modification with a Recycled Polymer and Surfactant Obtained from Oil Refining Waste.

The purpose of this study was to optimize the processes of wetting fillers by varying the content of such additives as a surfactant and polymer in bitumen-mineral compositions in order to achieve optimal performance. The cosine of the contact angle was used as a criterion for assessing the adhesion of the bitumen binder to the surface of crushed stone. The effect of the additives' concentration on surface tension and adhesive efficiency in binary and ternary bitumen compositions was studied.