Investigating Achilles tendon adaptation to mechanical load: a computational model integrating collagen fibre orientation heterogeneity.

Tendons are known to adapt their structural and mechanical properties in response to mechanical loading, but the precise mechanisms underlying this adaptation remain poorly understood. A previous study on rat Achilles tendons compared the effect of unloading (Botox injections and orthosis) with free cage activity (full loading) and revealed that unloading impaired the mechanical response and resulted in more dispersed collagen fibre orientations. The current study investigates tendon mechanobiology by integrating this experimental fibre data into a finite element model.

Development of an assessment tool for open reduction and internal fixation of midshaft ulnar fractures: A global delphi consensus study.

Objectives: In acknowledgement of the ongoing transition of surgical education from a time-based approach to competency-based curricula, this study aimed to identify key parameters for assessing the performance of surgical trainees in open reduction and internal fixation (ORIF) of a simple ulnar shaft fracture (AO/OTA classification 2U2A3.B).

Methods: A 4-round Delphi process regarding seven different orthopedic osteosynthesis surgeries was conducted with an international panel of orthopedic surgeons involved in surgical education.

Development and validation of the UserInvolve comprehensive toolkit for evaluating co-production in research: A guiding resource for researchers.

Background: Despite the evident trend in health research to emphasise co-production approaches, there is a lack of established, comprehensive and concrete strategies and evaluation methods to effectively guide and assess them. This project aimed to develop, validate, and test a toolkit designed to enhance and evaluate co-productions in mental health research. The toolkit includes practical evaluation tools, such as a structured questionnaire and tailored interview guides, to support the initiation of research projects and assess the involvement, process and impact of co-production efforts.

Assessment of Basic Orthopedic Surgical Skills in a Low-Cost Simulation-Based Setting: A Validation Study.

Introduction: Basic orthopedic surgery skills (BOSS) have been identified as critical in resident surgeons' training. Costs and limited evidence hinder integrating simulation training into resident surgeons' curricula. This study aimed to gather validity evidence for a low-cost simulation-based test to assess BOSS.

Factors influencing tooth loss over 9-11 years in young individuals with periodontitis.

Background: Herein, we aimed to identify factors associated with tooth loss over a 9- to 11-year period in young individuals with periodontitis, with a specific focus on the impact of patient compliance. The secondary outcome was to identify factors associated with discontinuation of active periodontal treatment.

Methods: This retrospective register-based cohort study included 446 patients under the age of 36, diagnosed with periodontitis at 2 periodontal clinics, between 2003 and 2009.