Improving Pleural Fluid pH Accuracy: A Quality Improvement Initiative.

Background: Fluid pH remains a standard test when evaluating pleural effusions. Studies recommend using a blood gas analyzer to measure fluid pH immediately after sample collection. Centralization of laboratory services at our institution led to migration of blood gas analysis to a single core laboratory with uncertain impacts on pH results.

College Marching Band Artists' Access to and Satisfaction with Healthcare Providers.

Objective: Approximately 27,000 college marching band (MB) artists in the United States could benefit from access to healthcare services and patient-centered care (PCC). The purpose of this study was to explore healthcare providers (HCPs) who MB artists have access to and the artists' perceptions of PCC.

Methods: We used a cross-sectional, web-based survey to explore which providers MB artists had access to.

The Emerging Mycotoxin 2-Amino-14, 16-Dimethyloctadecan-3-ol (AOD) Alters Transcriptional Regulation and Sphingolipid Metabolism and Undergoes -Acylation by HepG2 Cells.

2-Amino-14,16-dimethyloctadecan-3-ol (AOD) is commonly found in foods contaminated with , particularly cereals or fruits, and is structurally related to mycotoxins (fumonisins) and mammalian sphingoid bases, especially 1-deoxysphinganine (m18:0); therefore, it might enter systemic circulation and tissues upon dietary intake. Knowledge about what happens when cells are exposed to AOD is limited, but it has been reported to be cytotoxic and to induce vacuolization in HepG2 cells. We also found that AOD is cytotoxic for HepG2 cells, but even at a concentration where cell viability remained above 85% (5 μM), it altered 24 differentially expressed genes based on RNA sequencing-based transcriptomic profiling.

The Role of Axillary Lymph Node Dissection in Breast Cancer Patients With Residual Nodal Disease After Receiving Neoadjuvant Chemotherapy.

While sentinel lymph node biopsy (SLNB) in breast cancer patients with limited axillary disease undergoing upfront surgery is well-accepted, there are insufficient data supporting its safety with residual nodal disease (RND) following neoadjuvant chemotherapy (NAC). To evaluate axillary management and oncologic outcomes of patients with RND. A retrospective review comparing patients receiving SLNB to those receiving axillary lymph node dissection (ALND).