Endoscopic Submucosal Dissection of Large Gastric Hyperplastic Polyps: Clinicopathological Study From a Single Center.

Background Gastric hyperplastic polyps (GHPs) represent a subset of gastric polyps that are clinically problematic when large and they can cause persistent, low-grade bleeding or gastric outlet obstruction. Rare malignant transformation has been reported, albeit not in our experience. Methods We retrospectively studied the clinicopathologic characteristics of large GHPs (≥20 mm) excised by endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR) between 2013 and 2020 at a single institution.

Transforming Drug Therapy with Deep Learning: The Future of Personalized Medicine.

Personalized medicine represents a paradigm shift in healthcare, aiming to tailor treatment strategies to the unique genetic, environmental, and lifestyle characteristics of individual patients. This approach holds immense potential for improving therapeutic efficacy and minimizing adverse drug reactions. With the rapid advancement of artificial intelligence, deep learning has emerged as a transformative tool in pharmacology, enabling precise modeling of complex biological data and uncovering hidden patterns in patient-specific information.

Secondhand E-cigarette and Tobacco Smoke Exposure and Stages of E-cigarette Use in U.S 6th-12th Graders.

Introduction: Studies examining the association of secondhand exposures with e-cigarette use behaviors have been limited by indirect or incomplete measures of exposure. This study reports the prevalence of secondhand e-cigarette and tobacco smoke exposure among U.S youth and examines how robust measures of secondhand exposure correlate with e-cigarette susceptibility, ever use, daily use, and quit attempts.

Palliative use of lumen-apposing metal stents in tandem to alleviate malignant bowel obstructions in a patient with small-bowel adenocarcinoma with carcinomatosis.

Background And Aims: Duodenal stents or endoscopic gastrojejunostomy with lumen-apposing metal stents (LAMSs) are commonly used to treat small-bowel obstruction. However, endoscopic therapy for many regions of obstruction is less well-established. We describe a patient case with multiple areas of obstruction that was relieved with LAMS placement, creating gastroenteric and enteroenteric anastomosis.

Cancer Incidence and Mortality Across 43 Cancer Registries in India.

Importance: Cancer is a significant global health concern, with India ranking second in Asia and third in the world in terms of cancer incidence. Regular monitoring and updates on cancer statistics are vital for assessing the impact and burden of the disease and the effectiveness of cancer control measures.

Objective: To measure the recent patterns and trends in cancer incidence and mortality across 43 geographic regions in India from 2015 to 2019 and to provide estimates for 2024.