Glucagon-Like Peptide-1 Receptor Agonists Reduce Surgeries and Hospitalizations in Hidradenitis Suppurativa: A Multicenter TriNetX Cohort Study.

Background: Hidradenitis suppurativa is a chronic inflammatory skin condition frequently associated with type 2 diabetes mellitus and obesity. Glucagon-like peptide-1 receptor agonists have emerged as promising agents for managing type 2 diabetes mellitus due to their potent effects on glycemic control and weight reduction. Recent evidence suggests that glucagon-like peptide-1 receptor agonists may also possess anti-inflammatory properties, potentially making them effective in treating inflammatory conditions, such as hidradenitis suppurativa.

High rates of reoperation following operative fixation of open patella fractures.

Purpose: Patella fractures are common and may result in significant morbidity. Open patellar fractures are less common, and there are few investigations into their outcomes and complications. This study aimed to determine acute outcomes after operative treatment of open versus closed patella fractures.

'I Wanna Know What I'm Putting in My Body': Perceptions of Drug Checking Services and Supply Information Among People Who Use Drugs in Rhode Island.

Introduction: Drug checking services are emerging in the United States as a response to the rapidly changing drug supply. To inform the expansion of these services, it is critical to understand people who use drugs' perceptions of these programs and technologies. We explored perceptions of multiple drug checking technologies and supply communication among people who use drugs in Rhode Island.

Unveiling anticancer peptides; from the mechanisms of action to their development through artificial intelligence.

Cancer is a leading cause of death worldwide and a major burden on the healthcare system. Current treatment methods are limited as they have low selectivity, unspecific targeting and increasing multidrug resistance. Therefore, newer modes of therapeutic strategies need to be developed.