Comparative analysis of the World Health Organization Reporting System for Head and Neck Cytopathology and the Milan System for Reporting Salivary Gland Cytopathology.

Background: A comparative analysis of the International Academy of Cytology-International Agency for Research on Cancer-World Health Organization Reporting System for Head and Neck Cytopathology (WHO) and the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was performed.

Methods: A total of 2218 salivary gland fine-needle aspiration samples collected at the Institut Curie, Paris (1954-2022) were evaluated, with 1356 having histological follow-up. Samples were classified according to the MSRSGC (nondiagnostic [ND], nonneoplastic [NN], atypia of undetermined significance [AUS], benign neoplasm [BN], salivary gland neoplasm of uncertain malignant potential [SUMP], suspicious for malignancy [SM], and malignant [M]) and the WHO system (insufficient/inadequate/nondiagnostic, benign, atypical, neoplasm of uncertain malignant potential [NUMP], suspicious for malignancy [SM], and malignant [M]).

Application of the Milan and IAC-IARC-WHO Systems in diagnosing soft tissue and bone tumors of the salivary glands: The Institut Curie experience.

Background: Soft tissue and bone tumors of the salivary gland were compared using classic 4-tier, Milan System for Reporting Salivary Gland Cytopathology (MSRSGC), and the International Academy of Cytology-International Agency for Research on Cancer-World Health Organization (IAC-IARC-WHO) Reporting System for Soft Tissue Cytopathology.

Methods: The authors retrospectively analyzed 2219 salivary gland fine-needle aspiration (FNA) samples collected at the Institut Curie in Paris between 1954 and 2022. A total of 86 cases (3.

Wide-field quantitative micro-elastography of freshly excised human prostate.

Prostate cancer is a significant global health issue. To advance diagnostic and treatment procedures, such as image-guided needle biopsy, optical imaging methods offering high spatial resolution have been proposed. Optical coherence tomography (OCT) allows for detailed visualization of prostate microarchitecture in three dimensions; however, it does not reliably differentiate tumors from surrounding healthy tissue.

NGS coverage accurately predicts and () gene amplifications in a real-world non-small cell lung cancer cohort.

Background: Fluorescence hybridization (FISH) is the current standard for detecting gene amplifications, yet its low throughput and practical constraints call for alternative methods. This study evaluates next-generation sequencing (NGS) as a potential tool for accurately predicting gene amplifications.

Methods: We analyzed 66 primary non-small cell lung cancer (NSCLC) samples, tested by both NGS and FISH.

A community analysis of plant-parasitic nematodes on coastal Oregon golf course putting greens.

Plant-parasitic nematodes (PPN) are important pests affecting golf course putting greens. Recently PPN have become a pest of concern in the Pacific Northwest (PNW), but relatively little information exists on species present or their distribution across the region. A survey and community analysis of PPN across five independently managed golf courses in southwest Oregon was conducted.