Physical health and cognitive ability factors in predicting retirement adjustment based on machine learning approach: results from the China Health and Retirement Longitudinal Study.

Introduction: Retirement is one of the most significant status changes in an individual's later life. Physical health and cognitive ability are key predictors of retirement adjustment. However, studies have yet to investigate the role of different physical health and cognitive ability indicators simultaneously, and their non-linear association in relation to retirement adjustment.

Elevated PRDM13 Disrupts Photoreceptor Function and Survival in the Mammalian Retina.

Purpose: Retinal degeneration is a common cause of blindness, but there is a gap in our understanding of the molecular mechanisms causing degeneration. Dysregulated PRDM13 has been linked to retinal dystrophy, indicating a role for PRDM13 in the retina. PRDM13 knockout studies have shown that PRDM13 specifies amacrine cell fates, but no studies have shown the phenotypic and mechanistic outcomes of its elevated activity in the retina.

Carnivorous dinosaur lineages adopt different skull performances at gigantic size.

Theropoda is one of the most extensively studied dinosaur clades, including iconic carnivores such as Tyrannosaurus rex and Spinosaurus aegyptiacus. The clade includes the largest terrestrial bipeds ever described, including three lineages that independently achieved giant size: Megalosauroidea, Allosauroidea, and Tyrannosauroidea. Here, we investigate how increasing size influenced feeding performance by quantifying feeding-induced mechanical performance across numerous large theropods using 3D finite element analysis.

The OurFutures Vaping eHealth intervention to prevent e-cigarette use among adolescent students in Australia: a cluster randomised controlled trial.

Background: E-cigarette use among adolescents is a global public health concern. The efficacy of scalable prevention approaches is yet to be established. We aimed to evaluate the efficacy of a school-based eHealth intervention (OurFutures Vaping) to prevent e-cigarette use among adolescents.