Impact of respiration on abdominal pain thresholds in healthy subjects - A pilot study.

Objectives: Pressure algometry is a validated method for objectively quantifying pain sensitivity in musculoskeletal disorders, particularly useful for diagnosis and monitoring of treatment responses. However, its application to abdominal pain sensitivity remains insufficiently standardized, especially regarding the influence of physiological factors such as respiration. This study investigated the impact of respiratory phase (inhalation vs exhalation) on abdominal pressure pain thresholds (PT) to support the development of standardized assessment protocols.

Assessment of Vascular Density, Macular Layer Thickness, and Foveal Avascular Zone in Pseudoexfoliation Disease.

Prcis: Significant reductions were observed in macular vessel density and ganglion cell layer thickness in patients with XFG and XFS; suggesting these parameters may serve as early biomarkers for diagnosing and monitoring the progression of glaucoma.

Objective: This study aims to enhance early glaucoma diagnosis in Pseudoexfoliation syndrome (XFS) patients by assessing changes in macular vessel density and retinal layer thickness, and by investigating the relationship between these parameters and disease progression from XFS to pseudoexfoliation glaucoma (XFG).

Methods: This cross-sectional study involved 25 eyes from 17 XFS patients, 32 eyes from 21 early XFG patients, and 34 age- and gender-matched healthy controls.

Quantifying latanoprost-induced conjunctival hyperemia by anterior segment optical coherence tomography angiography.

Aim: To evaluate the mid-term effects of topical latanoprost 0.005% on vessel density (VD) of the bulbar conjunctiva using anterior segment optical coherence tomography angiography (OCTA).

Methods: Thirty-four eyes of 21 patients and 18 eyes of 9 healthy subjects were recruited as the treatment and control groups, respectively.

Characterization of cardiac sarcoidosis in Iranian patients using cardiac magnetic resonance and positron emission tomography imaging techniques.

Background: Cardiac involvement in sarcoidosis is associated with high mortality but is often underrecognized due to diagnostic challenges. Advanced imaging modalities like Cardiac Magnetic Resonance (CMR) and Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) are highly sensitive for detecting myocardial inflammation and scarring, aiding in the diagnosis and management of cardiac sarcoidosis. The objective of this study was to characterize the imaging features of cardiac sarcoidosis in Iranian patients using these advanced cardiac imaging modalities.

Pharmacogenomics in cardiac therapy: Personalizing treatment for heart health.

Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality worldwide. Genetics factors play a significant role in the development of CVDs, which may result from monogenic or polygenic influences. These genetic contributions can lead to various life-threatening conditions such as cardiomyopathies, aortopathies, dyslipidemias, and arrhythmias, many of which are associated with sudden cardiac death (SCD) in adults.